FOOLED BY FOOD LABELS?

We often think of food as healthy or unhealthy, good for you or bad. So the companies use this to their advantage in their branding and packaging, to give foods health haloes that suggest they are healthy, when the reality may be more complicated than that. Seducing claims such as ‘natural’ and ‘low fat’ lead many of us to overestimate how healthy a food is. It can also discourage us from reading the nutritional details on the back label.

What do labels really mean?

Organic: it’s easy to believe that ‘organic’ equals nutritious. But organic certification does not guarantee the nutritional quality of food – instead it states the production methods. A US study has suggested that when food is labelled ‘organic’, people tend to believe it contains fewer calories.

Superfood: the term ‘superfood’ has no regulatory approval and no accepted definition – it is more a marketing word than a health one. Regardless, it’s been shown to have a strong effect on consumers – 61 percent of us have bought something because it is labelled ‘superfood’, according to YouGov.

Low fat: ‘low fat’ doesn’t always equal healthy. In the UK this label means the product must have less than 3g of fat per 100g. But when producers take out fat they often pile in sugar. Studies have shown that a ‘low fat’ label can trick us into eating more.

Low sugar: similarly to the ‘low fat’ label, ‘low-sugar’ foods can be high in fat and calories. The ‘no added sugar’ label doesn’t guarantee a low sugar content. Companies use fruit juice concentrate as a sweetener, as it does not have to be labelled as ‘added sugar’, but it is essentially sugar.

Natural: this word evokes a sense of healthy, unprocessed food. The Food Standards Agency states that ‘natural’ should mean that the food is made up of ingredients produced by nature. Many contain chemicals renamed to be more appealing to consumers. ‘Carrot concentrate’, for example, is a highly processed ingredient that’s used as a yellow food colouring.

Labelling and digestion

When individuals think they have consumed more calories than they have, their bodies respond as if they have actually consumed more. In a 2011 study, milkshake was packaged in two different bottles. One was labelled ‘Sensishake’, claiming to be a low-calorie drink with 0 percent fat, no added sugar and 140 calories. The other labelled ‘Indulgence’ and advertised as a rich treat with 620 calories. Both drinks had 380 calories. The study measured the participants’ level of ghrelin, the ‘hunger hormone’, whose levels drop in the body after a big meal, signalling to your brain that you’re full. They drank ‘Indulgence’ milkshake and their ghrelin levels dropped three times than when they drank ‘Sensishake.’ The difference in ghrelin response is seen as consistent with what happens if the individuals really consumed drink with different calorie counts. The results are consistent with well-documented placebo effect.

Location, location, location

We are bad at estimating how many calories are in food, and labelling makes this even more difficult. It turns out location really is everything. Research suggests that when people eat at a fast food chain labelled ‘healthy’ (even if it isn’t), they greatly underestimate calories consumed compared to when they eat somewhere they believe to be ‘unhealthy.’ They may also order more side dishes, drinks and desserts when eating out somewhere ‘healthy’.

‘If I have a low-fat snack I can eat more of it’

If you have a salad for dinner, do you think you deserve a slice of chocolate cake? A front label only gives limited information and it’s important to read the ingredients list at the back. Even if you are trying to reduce the fat in your diet, eating foods with the fat swapped for sugar will not necessarily be better for you. A great way to eat better is to cook for yourself so you know exactly what you’re eating.

Reblogged BBC Food

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TREASURE IN CLAY VESSELS

pottery-ceramicTreasures in clay earthware vessels hidden, priceless gem, preserved to encourage you to hold on, endure by faith Jesus Name.

A rock collector named Rob once went on a dig and found a rock he described as “purdy and big.” He tried unsuccessfully to sell it, and when that failed, he kept the rock in his closet in the dark. “We have treasure in earthen vessels, surpassing greatness of power and will of God not from ourselves but from God. Although afflicted in every way, but not crushed; perplexed but not despairing; persecuted, but not forsaken; struck down, but not destroyed says .” 2 Corinthians 4:7-9 in the Bible. Rob had guessed the blue chunk of rock could bring as much as $500, but he would have taken less if something urgent came up like paying his power bill. That’s how close he came to selling for a few hundred dollars what turned out to be the largest, most valuable sapphire ever found. The blue rock Rob Cutshaw had abandoned to the darkness of a closet two decades ago known as “The Star of David” sapphire weighs nearly a pound, and could easily sell for $2.75 million. How many have a treasure hidden in the darkness of our lives, unaware of its immense value? God wants nothing more than for you and me to have full access to all blessings and rewards He’s already laid aside for us to have.bIt’s easy to live life unaware that God has set aside this treasure to have. I can often live in desperation, wondering when I’m going to get a break, questioning when God’s going to finally come through. So, how do we discover this fantastic treasure and let God take care of our needs? Sometimes, for God to meet our need we first plant seed for others.7759295-handmade-clay-jars-characteristic-of-central-java-indonesia

Many years ago, our church ministry was about to be kicked out of a school where we’d been meeting for Sunday service. While we had no idea what would happen, we continued to teach the Word and take care of each other like brothers and sisters in Christ should. I was still at Dallas Seminary, and one day I walked by a staff member there who casually said to me, “Oh, by the way, did you know that that small church on Camp Wisdom Road is getting ready to move, and they’re looking to sell?” Before the year was done, we moved to our permanent church home. Because we stayed diligent in fulfilling our calling as a ministry, teaching the Word and caring for each other, God revealed a wonderful treasure that was mere blocks from the school we had been occupying. God has called you to a mighty work as well. The hardships we face can be distracting, even paralyzing sometimes. But God wants to know whether our focus is on Him or on our hardships. When we stay diligent with what He’s given us, God will fill us to overflowing with even more down the road. Consider this example. If you wanted to purchase a particular amount of rice, the person behind the counter would pour that rice into a measuring pot or scale of some kind. But they would not fill it to the precise measure straight away; they would only go three quarters of the way up and then shake the pot and press on the rice. The reason for shaking is to both level out the rice and fill in any gaps formed underneath. In other words, because of the shaking and the pressing, you get more rice. That’s what God can do in the midst of your trouble; He lets life press down so He can “fill in the gaps.” AsEarthen_Vessel_thumb[1] 2 Corinthians 4:8 reads, “We are afflicted in every way, but not crushed; perplexed, but not despairing.” Most often, it’s in life’s darkness that God prepares us for His best. Lord, I ask You to give us peace, to weather the storms of life and relax in dark times, knowing You are with me. Fill me with a greater measure of Your courage, that I might stand boldly against the enemy’s attacks. Finally, I ask for patience as I wait for Your great treasures, both here and in the life to come. In Jesus’ Name, Amen.

TRUTH FOR TODAY:
Isaiah 33:6, “God is the stability of your times your wealth of salvation, wisdom and knowledge; The fear of the LORD is God Almighty’s treasure.”

RELATED RESOURCES:
If plagued with a lifetime of struggle, sickness or heartache, you likely cried out to God for help. When it seems like HE S’ not answering, what do you do? God’s great reward is often found in the darker places of your life. Learn to take eyes off circumstances and place them on the LORD. Get into living in service of God’z Kingdom. Get copy of Dr. Tony Evans’ Treasures in Darkness CD series.

CONNECT: 
Experience more Dr. Evans’ teachings, books and ministryn @ tonyevans.org.  Get copy of Treasures in Darkness by Dr. Tony Evans to celebrate new series, The Urban Alternative 5 CDs! Leave a comment on our website today, and we’ll randomly select 5 winners. We’ll notify each winner in the comment section by Monday, July 16, 2018.

REFLECT AND RESPOND:
What are some dark places you’ve been in recently? What’s one step you can take to move away from the darkness toward God’s intended treasure?

© 2018 by Dr. Tony Evans. All rights reserved.

Proverbs 31 Ministries thanks The Urban Alternative for their sponsorship of today’s devotion.

Proverbs 31 Ministries
630 Team Rd., Suite 100
Matthews, NC 28105
www.Proverbs31.org

RESURRECTION OF THE DEAD

30133Hebrews 9:27 says it’s appointed once to die in Bible yet people live again after a clinical death resuscitation with proof of their confirmed death certificate. Some assume verse means mankind dies ONCE ONLY so never lives after death. Yet Scripture shows Jesus’ resurrection brought life after death and Jesus lives in heaven. Christ was sacrificed once to take away sin He will appear a second time in the CLOUDS in Rapture to bring salvation. Also other physical resurrections happened in life prior to Christ’s resurrection in the Old Testament showing a young boy died and was brought back to life by Elisha in 2 Kings 4:19-37. Another dead man was revived when his body touched the bones of prophet’s Elisha’s grave in 2 Kings 13:21. Individuals in Old and New Testament died but raised from death by Jesus and disciples. Many people were raised after Christ’s death, Resurrection God brought them back to life in Matthew 27:52-53, they went back to their homes, where many people saw them including their miracle experience for their relatives and friends reunions. The Bible account of these people God resurrected at Christ’s death eventually died again and their families buried them again. All other saints who died wait in graves to be resurrected to life in glorious spirit body. They did not die ‘once only’ but lived after resurrections and died second time later. They lived the rest of their resurrected physical lives and died again, buried, awaiting resurrection to spirit life upon return of Jesus Christ in Rapture. Proverbs 18:21 in Bible says death and life are in mouth so choose life. Those who do believe in Rapture of Daniel 12 and 1 Corinthians 15:50-53 go to God in heaven before the Great tribulation starts. The others stay asleep in grave until a thousand years after Millineal reign of Jesus and raised so their spirit soul after death does NOT go to heaven to be with God for saying Ecclesiastes 9:5 that dead know nothing. They quote John 3:13, none ascends into heaven only Jesus who came down from heaven or Jesus Christ referred to death as sleep in John 11:12-15. But Enoch and Elijah went ALIVE into heaven so those left behind’s flesh and spirit stay ASLEEP in grave. Those in God in Christ who believe in Rapture are resurrected by Jesus in Rapture alive into heaven.

Raised From Death in the Bible

People Raised From the Dead

The widow of Zarephath’s son was also raised from death. The prophet Elijah was at house of widow in Zarephath when the woman’s son died. She said Elijah brought God’s wrath for her sin.

She carried the boy into the upper room where he was staying, Elijah laid him on a bed and stretched himself on the body three times. He cried out to God for the boy’s life to return. God heard Elijah’s prayer and child’s came back to life and Elijah carried him downstairs. The woman declared prophet a true man of God and his words to be true in 1 King 17:17-24.

Shunammite Woman’s SonElisha Heals Shunammite Woman's Son

Elisha, the prophet stayed in the upper room of a couple in Shunem. He prayed for the woman to bear a son, and God answered. Several years later, the boy complained of a pain in his head then died. The woman went to Mount Carmel to Elisha, who sent his servant ahead, but the boy did not respond. Finally, Elisha went to see the dead boy. He cried out to the Lord and laid himself on the dead body,  mouth to mouth, eyes to eyes, hands to hands. The boy’s body grew warm so he sneezed seven times and opened his eyes. Elisha presented the boy back to his mother, she fell and bowed to the ground in 2 Kings 4:18-37.

Resurrection of Israelite ManValley of Dry Bones

Elisha the prophet died and was buried in a tomb. Moabite raiders attacked the Israel in spring interrupting a funeral. Fearing for their own lives, the burial party quickly threw body into Elisha’s tomb. As soon as body touched Elisha’s bones, the dead man came to life and stood up on his feet. This miracle was a resurrection from grave into a new life in 2 Kings 13:20–21.

Widow of Nain’s SonJesus raising the widow's son at Nain

In a village of Nain, Jesus and disciples encountered a funeral procession. Only son of a widow being buried. When Jesus saw her, his heart went out to her. He touched the bier that held the body so pall bearers stopped. When Jesus told the young man to get up, the son sat up and began talking. Jesus gave him back to his mother so people were astonished Praising God, they said, “A great prophet has appeared among us. God has come to help his people” in Luke 7:11–17.

Jairus’ DaughterJesus raised the dead daughter of Jairus

When Jesus was in Capernaum, Jairus, a leader in the synagogue, begged him to heal his 12-year-old daughter because she was dying. On the way, a messenger said not to bother because the girl had died. But Jesus said to Jairus, “Don’t be afraid; only believe, and your daughter will be healed.” Jesus arrived in a house to find mourners wailing outside. When he said she was not dead but sleeping, they laughed at him. Jesus went in, took her by the hand and said, “My child, get up.” Her spirit returned and she raised to life again. Jesus told parents to give her something to eat but not tell anyone what happened in Luke 8:49–56.

Lazarus was raised by Jesus Tomb of Lazarus

Jesus’ friend Lazarus was very sick so Martha and Mary sent for Jesus to come heal him in Bethany. Jesus delayed so He did not arrive before Lazarus died. Jesus stayed two more days but later arrived in Bethany when Lazarus had been in the tomb four days. Martha met them outside the village, where Jesus told her, “Your brother will rise again. I am the resurrection and the life.” They approached the tomb Jesus wept. Jesus ordered the stone rolled away, saying, “Did I not tell you if you believe, you will see the glory of God?” Raising His eyes to heaven prayed aloud to Father God. He commanded Lazarus to come out and he did so walked out, wrapped in burial cloths in John 11:1-44.

Jesus Christ was raised ALIVEThe Resurrection of Jesus Christ

After mock trial Jesus was scourged and taken to Golgotha outside Jerusalem by Roman soldiers nailed Him to the Cross on Friday and His body was put in the tomb of Joseph of Arimathea. So tomb  was sealed and soldiers guarded place. Sunday morning, the stone was rolled awayand empty and angels said Jesus raised from the dead. He appeared first to Mary Magdalene and to his disciples plud many others around the city told in Matthew 28:1-20; Mark 16:1-20; Luke 24:1-49; John 20:1-21:25.

Saints in JerusalemResurrection

Jesus Christ died on cross as earthquake struck, breaking open many graves and tombs in Jerusalem. Jesus’ resurrection from death raised Godly people raised to life appeared to many in the city in Matthew 27:50-54.

Tabitha or Dorcas, Peter raisedPeter Raises Tabitha

Everyone in city of Joppa loved Tabitha. She was always doing good, helping the poor, and making garments for others. One day Tabitha named Dorcas in Greek grew sick and died. Women washed her body then placed it in an upstairs room. They sent for apostle Peter, who was in nearby Lydda sent all from room, Peter fell to his knees and prayed. He said to her, “Tabitha, get up.” She sat up and Peter gave her to friends alive. So many people believed in Jesus because of it in Acts 9:36-42.

Eutychus raised by Paul Paul raises Eutychus from death.

In a packed third story room in Troas a young man sitting on a window ledge fell to death during sermon by apostle Paul. Fell from the windowsill a young man Eutychus dozed off,falling out of the window to his death. Paul rushed outside and threw himself on lifeless body. Immediately Eutychus came back to life. Paul went back upstairs, broke bread, and ate, people saw Eutychus alive again in Acts 20:7–12. So many people in modern times are raised alive from the grave in many countries today. You tube videos record testimonies of millions of people raised from death all over the world. So Resurrection Spirit of God in Christ is still at work today in all countries because Jesus is the same Yesterday, today and forever. So people from all nations died more than once because Jesus tarried. Some will never die before Rapture if the CLOUDS takes place so Jesus comes sooner. No matter when Rapture takes place people alive will join those raised alive from graves.

hebrews-9-27-free-bible-verse-desktop-wallpapersScriptures is very clear out of soul body, buried goes to Heaven immediately if a believer or to hades or hell if not. When Lazarus died, the angels carried him to Abraham’s Bosom. He saw and talked to rich man across the Great Gulf and in torment and pain in eternal judgement in hell. In the Book of Revelation the souls of those killed during the 7 years of Jacob’s Trouble of Great Tribulation, were under the Altar of God in heaven talked to God and God talked to them. The asked how long was it going to be before God avenged their death and God replied they had to rest a little longer until others were slain as they were. They did not wait in a deep sleep in the grave. When the Rapture happens, Jesus will bring the souls of those who had died with Him and Jesus will call their glorified bodies up from the grave to reunite with their souls in the clouds. Those who are alive, will be translated like Enoch was in Genesis and join Jesus in the clouds. Scripture is clear on this so we should not contradict Word of God. All who believe death is ONCE ONLY remain asleep in graves on earth until the MILLENNIAL second resurrection of all dead after Jesus’ rule and Reign on earth. They do not believe God can take their Spirit soul to heaven so GOD let’s them remain asleep in the graves never enjoying joy of heaven as idea comforts loved ones to know dead person is still around just sleeping in a grave. This is in line with concept of those left behind on earth saying flesh and blood cannot inherit the kingdom of God. They are left behind on earth as God grants them the permissive will belief because of not thinking God changes HIS mind at times in Scripture to rise or live after death. Hezekiah was appointed to die but he refused to die so God changed HIS mind and extended his life 15 years. As Jesus said later no man ascended into heaven in John 3:13 in a manner He did. Enoch went alive into heaven, Elijah went to heaven alive but not in the grand global style Jesus did as sent off by disciples on Mount Olives. The faithful Christians in Christ will be resurrected into spirit life by Christ as their First of the firstfruits in rapture. Saints whose body in graves AWAIT their resurrection 1 Corinthians 15:20 – 23 will go in the Rapture. Their Lord and Master Jesus built mansions for them to go into heaven before the GREAT TRIBULATIONS of mark of the beast starts. It is important to make up ones mind because whether you believe it or not Rapture will take place as days Noah’s family was saved in the flood. it is appointed unto man to die once Lot was saved in Sodom and Gomorrah from the fire so GREAT TRIBULATIONS of endtimes from the EARTHQUAKES and unseen evil is too unbearable. But those who prefer to stay left behind are allowed by God to do so. Both beliefs of two groups of Rapture and Left Behind are valid for its not exclusively only one correct answer. Jesus said two will be together and one will be taken but the is left behind. In maths correct answer is accepted as long as you can prove your method at arriving at the right answer. In the same way God let’s those whose standpoint in Bible agrees with Rapture point of view go to heaven and those who stand on a left behind perspective left on earth accordingly. Rapture is coming for those AWAITING Jesus in the CLOUDS but those who prefer SLEEP in graves will be left behind until after the 1000 years of Jesus Rule and reign. It is a choice of each person to decide if they prefer Rapture or want to stay asleep in the grave until after Jesus’ Millennial Resurrection of the dead for judgement. Those taken to God into heaven receive REWARDS for their service for God but others will stay asleep until after 1000 years rule of Jesus before being judged. So Bible says, according to your faith be it into you because God does not force people against their will to resurrect in glorified body to HIS physical Presence in heaven. SO UNLESS YOU BELIEVE IN THE RAPTURE YOU WILL NOT EXPERIENCE IT. The Resurrection of Jesus is different from all resurrections because Jesus’ resurrection is first “permanent” resurrection. All other resurrections in Bible were “temporary” so those raised to life died again Lazarus died twice but Jesus rose and never died again. This is why, He is firstfruits of all those “fallen asleep” in 1 Corinthians 15:20. Jesus’ resurrection justifies us in Romans 4:25 ensures eternal life because Jesus lives we will have eternal life in John 14:19. It is good to know death is not end of life so believers mourn with hope of eternal Resurrection in Christ Jesus. Father God our Comforter comforts through Holy Spirit to bear grief, sorrow for a season of crying and tears during passing into Glory. Yet we have full assurance loved ones will rise again in Christ’s Rapture and be reunited in the Presence of God in heaven. Then later dwell with God on earth physically when New Jerusalem comes down to Israel under Christ Jesus our KING of King’s rule forever. There will be no more tears, sorrow, pain or grief for God wipes all our tears away to live forevermore in Eternal joy. Death is painful yet we have hope of living again in joy in resurrection of Jesus Christ. Carletonville mortuary in South Africa where the woman was found aliveA South African woman was discovered alive in a morgue after being declared dead in a car crash. The woman was found breathing by mortuary technicians several hours after being certified dead by paramedics at scene of pile-up outside Carletonville, southwest of Johannesburg. We followed our procedures – we’ve got no idea how it happened,” Distress Alert operations manager Gerrit Bradnick told AFP. The crew is absolutely devastated – we’re not in the business of declaring living people dead, we’re in the business of keeping people alive.”The unnamed woman from Gauteng “showed no signs of life” following the traffic accident in the early hours of 24 June, Mr Bradnick added. Carletonville mortuary in South Africa where the woman was found alive. She was found alive in morgue fridge many hours after the crash in which victims’ car rolled, throwing her out of vehicle. All the right checks were done: breathing, pulse so patient declared deceased, Mr Bradnick said. After being discovered alive, the woman taken to Carletonville hospital is now recovering. “Paramedics are trained to determine death, not life” a source at Carletonville mortuary told Sowetan newspaper. Other deaths came alive:-

Pastor Daniel Ekechukwu died and also came back to life in a basement room of a church at Reinhard Bonke crusade in Nigeria, Africa. By prayer and massage to soften dead body from rigor mortis suddenly Daniel sneezed and arose with a jump. Between 3:50 and 5:15 PM on Sunday, Daniel who died Friday night around 10:00 PM slowly became fully coherent over the next few hours. The video of his testimony is below to see. A report on the website of Christ for all Nations declares: Three days Daniel was in a mortuary, did not breathe, his heart stopped beating. In hot climate, without ice chamber was injected with chemical to keep back mortification. Corpse was carted around for hours, pulled about, and lay in airless narrow coffin hours completely dead with death certificate. This public event was demonstration of revival from death by God in Jesus Name through wife Nneka’s faith. Her incurable faith prevented Daniel’s burial to bring him because she was convinced God will bring him back to life. She said Reinhard Bonnke as a man of God in the atmosphere of faith he ministered, this miracle was possible. The faith of Nneka dictated the whole event and her faith was honoured by God. She stood on the word of God that women receive their dead alive in Bible. Pastor Ekechukwu shares his testimony of his story of what happened when he was in heaven and saw hell. Now Pastor Daniel’s message is repentance of the church to prepare the church to stand before Jesus, and many have indeed repented after hearing his testimony live in real holiness. Ministry of Reinhard Bonnke in Nigerian crusade and in all the world share his testimony on TV and travels to share testimony.

DEVIL HAS NOTHING IN ME

downloadJesus said, “the devil has nothing in me” in John 14:30 while chatting with His disciples. There is nothing in Jesus to connect the devil as point of contact because Christ has no sin in Him says John 18:38 so the devil has no power over Jesus. And the prince of this world has nothing in our Lord and Saviour Jesus for the devil was completely defeated in the temptation and departed from Jesus. So turned his attention to God’s Children to attempt to destroy and separate them from love of God. The devil does not want people to know about his plans to deceive or fool people that he is a murderer from the beginning. There is no truth in the devil so he lies and transforms himself into angel of light. And satan does not like God’s TRUTH so uses the workers of lawlessness in Matthew 7:22–23 to try to convince people to rebel against God. It is done in subtle ways with good motive ending badly in the long run. Since the beginning was thrown out from heaven so comes to cause havoc on earth. Many people are unaware of his strategies so do not realise his impact on their lives. They think they just have bad luck or a bad misfortune in life. However, there is a spirit at work through principalities and powers plus spiritual wickedness in high places. Strategy used is so effective and harmless but things later fall apart years later after the damage is done. At first things seem normal so do not think anything of the choices made. However with hindsight, the danger signs were there all along but not understood. The spirit at work is not realised until after people learn what is going on in their lives is discerned. The warning is given by Jesus to ensure His followers have nothing of the devil in them. So people have no idea the devil has anything in them because of how he is portrayed on TV, media, films and in the church.081005-john-14-1-31-28-728 Yet there is indirect effect through decisions made daily that can mean the devil has something in people. Through deception and promises of better life or enjoyment choices often made show consequences different from expectations. A careful look at life at a deeper level reveals the compromises made unawares. Example is seen in the restlessness and distress although doing the right thing. This is a direct result of unseen realms through supernatural understanding the mind’s eyes become opened to recognise God’s way. Once transferred from kingdom of darkness into God’s Glorious Kingdom of Light, one begins to ‘understand the reality of actions of the devil. Especially in a society that celebrates the devil as a harmless fun its implications are harder to comprehend. The devil is represented by serpents in physical, spiritual forms, shapes or types well-known globally. It is the symbol of Egyptian rulers who wore them in their golden emblems. The serpent is worshipped in temples and kept as magical protection alive in some homes. It is given to those seeking wealth through occulted means hoping to vomit money automatically as it is venerated. DNA blood incisions on body of cult members meeting annually reinforces satanic celebrations that God forbids. One major characteristic is the effects of spiritual attacks compounding the original problems seeking help with. While it seems as if childless couple has a baby after consulting shrine, there is a bizarre ritualistic taboo to observe for a survival of that baby. The rules are to be maintained throughout the life of such a baby by the parents who got help from a temple. The child is dedicated to a god for life together with their whole family who observe rituals in secret because a church will excommunicate and shun them if their secret deeds come to light. IMG_20180703_224623A child taken to both a shrine and God’s Church is baptised, confirmed and takes communion plus get married in church. So many people have this sort of history and over time when they no longer pay homage to shrines experience adversity without knowing why. Later some learn about their family and do deliverance by casting out demons from their lives. Fully become believers and devote lives exclusively to God seriously with total commitment to God. They break free without fear of the past because Jesus lives in them now so in Christ they live, and move and have their being. Jesus destroys all works of the devil in their lives and delivers them from all their destructions. Strong faith in God in Christ is absolutely the only way to ensure protection against an occult background. The ritual tokens including serpents must be gotten rid of by a deliverance pastor. Housecleaning of symbols, images or memories kept of serpent, shrine is burnt as Apostles did burning charms, magical books, rings in the book of Acts of the Apostles. Dreams are another source of serpent attacks to try to put fear into people at night. The delivered person has a nightmare dream of serpents always in different forms of threatening them or slathering nearby. Regularly dreaming of seeing serpents is signs of attacks to put fear, confusion, hopelessness into a person. The devil transforms as serpent triggers fear and put disease in a person by biting them or marries them, kissing them or surrounding them in dreams. It is a serious attack so break it because Jesus crushed the serpent under His feet in Jesus Name for all believers. Some do vomit things eaten, drunk or smeared on them for ‘protection.’ Fast and pray for God to rebuke satan from your right hand in Jesus Name. You must now be under new management of Jesus Christ by abiding in God in Christ Jesus. Your life must be hidden in Christ in God so the devil has to try to fight Christ in you.the-devil-s-got-nothing-on-me-my-friend Once you give your life to Christ with an access to all areas of your life, Jesus takes full control of your life and family. As you and your household serve God by abiding in Jesus and His Words in the Bible, the devil will run from you. The devil seeks those to destroy like roaring lion so does not access everyone. Total dedication to Jesus as your first love, hot on fire for God is important. Note that the more faithful you are serving God so is the devil drawn to strong believers to try to sabotage God’s Spirit at work in them.Whenever God’s Children meet the devil shows up to create mayhem to lure vulnerable ones. Abide in Jesus and let Jesus” Words abide in you so ask Jesus your desire to remove serpent from you so it is done for you in John 15:7. Pray to God in Jesus Name to take care of your life and come to God’s Throne boldly in Jesus Name through the Blood of Jesus. Knowing how to pray is a conversation with God to reveal HIS strategic secrets to you in advance through His words in the Bible. Abiding in God in Christ and His Word in us is a blessing to ask for what we desire in line with God’s word. Abiding in Jesus means that His desires become your desire so the devil has nothing in you. It is God’s will that all must have Spirit of God in them and to prophecy. Bible Scripture says pray directly to God’s Throne room according to Jeremiah 3:33. 1. Praise God. 2. Thank God. 3. Pray for forgiveness 4. Ask for God’s Blessing, Favour, Intervention, Healing and deliverance. 5. Intercede for others. Attend a Bible believing church to worship God called to be active participant member not merely an observer.  We can make a difference in Jesus Name and give Glory to God.

WORLD ASTEROID DAY PLAN

Asteroid

World Asteroid Day plans to work together to protect Earth from collisions. A scientist hopes to send a spacecraft to a small asteroid to develop methods of protecting our world from near-Earth objects has said it is crucial for scientists around the world to work together to address the threat of asteroids. The Asteroid Impact Mission looks to ‘deflect asteroids’ from hitting the earth and causing damages. Professor Ian Carnelli said, “This is a once-in-a-lifetime chance and we should do it” to save mankind and planet earth. Speaking on World Asteroid Day, aims to increase awareness of asteroids and extra-terrestrial objects, the European Space Agency’s Professor Ian Carnelli issued an appeal for British companies to invest in the candidate mission. He said: “We all agree this is an example of good background work and we need to take threats seriously and do something about it. “It is really the natural threat we can predict and possibly prevent so I think it is a no-brainer really.” Asteroid collision could be catastrophic for life on Earth. Professor Brian Cox will be leading the 48-hour broadcast to know if there is an asteroid on its way and how we can do something about it. “It also offers an excellent opportunity for the sort of international cooperation sadly lacking in the wider world. Mr Carnelli said he would been very keen to hear from British companies looking to invest in the projects, explaining: “We have British scientists involved but no investment from British industry.” Mr Carnelli is spearheading work on the Asteroid Impact Mission (AIM), which would see a satellite send to a binary asteroid system, consisting of Didymos, which is 800 metres in diameter, and a small, 170 metre object, informally known as the Didymoon.

Jan Woerner

ESA director Professor Jan Woerner will be at the event AIM, which Mr Carnelli hopes will launch in October 2020 assuming it gets ESA approval. It would take high resolution images of asteroids and attempt to build detailed maps of its surface and interior structure and beam it back to Earth. AIM would be Europe’s contribution to larger Asteroid Impact Deflection Assessment Mission (AIDA), a collaboration between ESA and NASA. Four months after AIM, NASA would launch its Double Asteroid Redirection Test (DART), which would crash into the asteroid, with AIM then measuring how much its trajectory had been altered as a result. Late Professor Hawkins described asteroid collisions as one of the major threats to intelligent life in our universe.” An steroid event   saw an object most scientists believe was an asteroid explode in the skies above Siberia in 1908. Professor Brian Cox hosts a 48-hour global broadcast about asteroids and space. Featured guests include musician Peter Gabriel, former Queen guitarist, astrophysicist Brian May, Professor Richard Dawkins, Canadian astronaut Chris Hadfield and Professor Jan Woerner, director of the European Space Agency. Former NASA astronaut Tom Jones commented: “Asteroid Day is a great opportunity to invite the public to learn more about the hazard from near-Earth asteroids, to invite their support of international efforts to discover and head off rogue asteroids. “We study asteroids to protect Earth to protect valuable resources for future exploration toward Mars.” The World’s Asteroid Day team is planning to work together to protect the Earth from such collisions. A scientist hopes to send a spacecraft to a small asteroid to develop methods of protecting our world from near-Earth objects has said it is crucial for scientists around the world to work together to address threat of asteroids. The Asteroid Impact Mission looks to ‘deflect asteroids’ from hitting the earth and causing damages. Professor Ian Carnelli said, “This once-in-a-lifetime chance hopes to save mankind and planet earth and aims to increase awareness of asteroids and extra-terrestrial objects. The European Space Agency’s Professor Ian Carnelli issued an appeal for British companies to invest in the candidate mission. He said: “We all agree this is an example of good background work and we need to take threats seriously and do something about it. “It is really the natural threat we can predict and possibly prevent so I think it is a no-brainer really.” Asteroid collision could be catastrophic for life on Earth according to Professor Cox.

Professor Brian Cox

Professor Brian Cox will be leading the 48-hour broadcast “Then if we know there is an asteroid on its way we can do something about it. “It also offers an excellent opportunity for the sort of international cooperation which is sadly lacking these days in the wider world.” Mr Carnelli said he would been keen to hear from British companies looking to invest in projects, explaining: “We have British scientists involved but no investment from British industry. Mr Carnelli is spearheading work on the Asteroid Impact Mission (AIM), which would see a satellite send to a binary asteroid system, consisting of Didymos, which is 800 metres in diameter, and a small, 170 metre object, informally known as the Didymoon. Collisions are major threats to intelligent life in the universe so International Asteroid Day, held on 110th anniversary of Tunguska event, that saw an object most scientists believe was an asteroid explode in the skies above Siberia in 1908. So Professor Brian Cox’s 48-hour global broadcast about asteroids and space featured guests include musician Peter Gabriel, former Queen guitarist, astrophysicist Brian May, Professor Richard Dawkins, Canadian astronaut Chris Hadfield and Professor Jan Woerner, director of the European Space Agency. Former NASA astronaut Tom Jones also commented: “Asteroid Day is a great opportunity to invite the public to learn more on hazard from near-Earth asteroids, and invite their support of international efforts to discover and head off rogue asteroids. “We study asteroids to protect Earth and to protect valuable resources for future exploration toward Mars.”

TWO EDGED-SWORD OF GOD

Map Israel TodayGod’s two-edged word is powerful and compared to God’s word transforming lives cutting edge tool that removes sin from a person. God’s Sword Fights His people against enemies. Believers call upon God to, “Gird your Sword on your side you Mighty One and clothe yourself with splendour and majesty in Psalm 45:3. God is the Sword of defence of His people. God’s Sword gives justice sword against the violence, wrath, and vengeance of enemy. Father God is love but as Jehovah Nissi the Mighty ONE in battle defends His Own. God’s is loving, and protective with great plans for His justice. God destroys but protects all on His Side so nourishes and saves them in His Own way. So Sword of God’s Glory is seen through Israel heritage and landmarks. Over the years the shape of the map of Israel covenanted from one end to the other encompasses the chosen domain of God on earth. This landmark dwindling through conflict is held by  “Blessing Israel the people saved by the LORD Who is Shield, Help and the Sword [chereb] of your Majesty (gaavah) says Deuteronomy 33:29. The Children of God in Canaan conquered giants as Moses reminded them LORD YAHVEH is their protector and a Shield and their salvation yasha tool HE used to save them by His word as a Sword. It is God Sword that desolates, destroys or dries up wetlands into droughts. So the Sword of Deuteronomy 33:29 is a sword of gaavah or glory, triumph, excellency, and majesty as weapon used to defend and proclaim name of LORD YAHVEH. The people of Israel see God’s Majestic warfare and salvation on their behalf. God’s He greater goal is salvation plan through Jesus Christ to deliver people defeat and emotional slavery. The Glory of God is manifested and also restored because God raised Moses for this purpose to show My POWER and My NAME to be proclaimed in all the earth according to Exodus 9:16. When persuasions and negotiations does not work God wields His sword a final time to bring judgements upon the earth. So salvation from eternal death was free but paid for by the sacrifice of an innocent lamb Jesus Christ. Preparing for the Passing Over of the Angel of Death  (1911), by Sylvanus Stall

 

STOP BLOOD CLOTS IN BODY

Venous thromboembolism (VTE) blood clots diagnosis is a serious preventable medical condition. So its important to know VTE or deep vein thrombosis (DVT) happens to anybody at any age and causes serious illness, disability and in some cases, death. VTE is prevented and treated if discovered early. PE in SCD patients is etiologic factor in patients who develop respiratory symptoms. Xray imaging procedure scans chest for blood clots treated with full-dose anticoagulation. Diagnosis of venous thromboembolism by positive Duplex ultrasound, ventilation-perfusion scan, or computed tomography angiography in most cases. Radiology reports for patients with documented history of anticoagulation treatment venous thromboembolism cases. This criterion verifies the high specificity history venous thromboembolism. So thromboembolism data collected on date of diagnosis, recurrence, site of thrombosis, central venous catheter-related status. Additional triggering factors includes oral contraceptives, pregnancy, cancer, hospitalization, surgery recorded. Hospitalization associated clots defined by venous thromboembolism occurring 24 hours after admission or within 90-days after discharge. Disseminated intravascular coagulation (DIC) is a condition in which blood clot forms thrómbōsis  clotting inside the blood vessels obstructing flow of blood through the circulatory system. If a blood vessel vein or artery is injured, the body uses platelets thrombocytes and fibrin to form blood clot to prevent blood loss. Even when blood vessel is not injured, blood clots form in body under certain conditions. The blood clot or piece of clot breaks free, travels around body as embolus in body blocking small blood vessels. Symptoms are chest pain shortness of breath, leg pain, problems speaking, or moving parts of body. As clotting factors and platelets used up bleeding occurs with blood in urine, blood in stool, bleeding in skin. Complication include organ failure. Red blood cells are principal means delivering oxygen (O2) to body tissues via blood flow circulatory system. RBCs take up oxygen in lung released into tissues squeezing through body’s capillaries. Blood clot blocks circulation causing severe pain or bruising mark on leg.  Treatment for a pulmonaryembolism is at the hospital to treat underlying causes of deep vein thrombosis. This starts with anticoagulant medications asheparin and warfarin to stop blood clots from returning. Pulmonary embolism occurs as clump of blood clot gets wedged into artery in lungs. Blood clots from leg condition deep vein thrombosis (DVT). A catheter is inserted into vein in the groin upper thigh or arm and threaded to clots in the lung. The doctor may use catheter to remove clot or deliver medicine to dissolve it. Rarely, surgery is needed to remove the blood clotClots block oxygen flow 2.4 million erythrocytes produced per second in human adults affected. Blocks red cells developing in bone marrow circulating 100–120 days in the body before component recycled by macrophages. Circulation takes 60 seconds or one minute and a quarter of the cells in human body are red blood cells. And the blood volume is 40% to 45% is red blood cells. Blood related conditions are critical life situations so must be taken urgently, extremely seriously. Every second counts and they must have continous oxygen supply during crises. The blood clots can appear incredibly quickly, due to a number of factors like change in temperature. It causes a number of problems in the body and causes issues heart attacks. If found during routine check ups clot dealt with before obstructing oxygen in red blood portal veins or arteries.S_0917_deep-vein-thrombosis_M17501.2e16d0ba.fill-767x511

Deep vein thrombosis (DVT) occurs if a blood clot (thrombus) forms in one or more of the deep veins in body, usually in legs. Deep vein thrombosis causes leg pain or swelling occur with cramps or no symptoms. Deep vein thrombosis develops if certain medical conditions affect blood clots. It happens if not mobile for long time after surgery confined to bed. Deep vein thrombosis is serious because blood clots in veins break loose, travel through bloodstream and lodge in the lungs blocking blood flow oxygen by pulmonary embolism. A lack of fresh oxygen from lungs causes breathing difficulties and shortage of breath so life threatening. Treatment is for 5-7 days or typically for 3-6 months, though blood thinners are continued for life if clotting disorder increases risk of another clot. After seven days, the clot is unlikely to be completely resolved so total time taken depends on the size of the clot. Most blood clots occur in lower legs and form when an individual is inactive for a lengthy period of time. A blood clot may develop in a patient’s leg after spending hours sitting or cramped on a plane. The symptoms experienced vary based on a size of clot, bigger clots are more painful than a smaller-sized ones. Those who have a blood clot in an arm or leg can experience swelling and tenderness. If the clot is small, minor calf swelling can occur but bigger blood clots cause whole leg or arm to swell. Those who have a clot notice a warm sensation or the affected area may turn bluish in color. The symptoms of a deep vein thrombosis signs and symptoms can include: Swelling in the affected leg. Rarely, there’s swelling in both legs.

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  • Pain in leg often starts in calf and feels like cramping soreness.
  • Red or discolored skin on the leg.
  • A feeling of warmth in affected leg.

Deep vein thrombosis occurs without noticeable symptoms sometimes. See a doctor if developed signs or symptoms of deep vein thrombosis, contact doctor. If developed the signs or symptoms of a pulmonary embolism a life-threatening complication of deep vein thrombosis seek immediate medical attention.

Pneumonia is also an inflammatory condition of lung affecting primarily the small air sacs called alveoli. At the end of the breathing tube of lungs, clusters of tiny air sacs become inflamed and fill up with fluid. Symptoms include some combination of dry cough, chest pain, fever, and trouble breathing. This can be triggered by the blood clot blocking wind pipes of lungs making it difficult to breathe without an oxygen tank or oxygenator. Pneumonia is often caused by infection with viruses or bacteria, by other microorganisms, or medications and conditions such as autoimmune diseases. Risk factors include lung diseases: cystic fibrosis, COPD, asthma, diabetes, heart failure, a history of smoking, inability to cough due such as following a stroke, or weak immune system. Diagnosis is based on symptoms and physical examination. Chest X-ray, blood tests and culture of  sputum may help confirm a diagnosis. The disease is classified by where it was acquired within community, hospital, health care associated pneumonia. Vaccine prevent some types of pneumonia, prevention methods include handwashing and not smoking. Treatment depends on the underlying cause. The pneumonia due to bacteria is treated with antibiotics. In bacterial pneumonia, the white blood cell count high but falls in severe cases. In viral mycoplasmapneumonia white cell count is low or normal but severe pneumonia cases hospitalized. Oxygen therapy is used if oxygen levels are low.

The warning signs and symptoms of a pulmonary embolism include:

  • Sudden shortness of breath
  • Chest pain or discomfort worsens when taking deep breath or cough
  • Feeling lightheaded, dizzy, fainting
  • Rapid pulse rates
  • Coughing up blood
  • Loss of appetite

People sometimes in certain extreme cases need the red blood clots removed surgically or medication, treatment by leaches work effectively. Blood thinning medication of aspirin or medical doctor prescribes medicines to treat patients. It must be treated urgently to stop lungs running out of air due to blocked clot as red blood clot in lungs causes shortage of breath or no blood circulation death. Respiratory circulatory system of blood clots produces blood poisoning from the decomposing blood matter. The blood is exchanged using centrifugal transfusion to replace coagulated blood. If it’s done early saves lives but delays of waiting for machine worsen patient’s survival. A patient must seek help early so as not to self – sabotage essential treatment for life because life is in the blood. IMG_20180627_101138Those with sickle cell disease (SCD) have signs of the disease during the first year of life, around 5 months of age. Symptoms and complications of SCD are different for each person and can range from mild to severe. The reason infants don’t show symptoms at birth is because baby or fetal haemoglobin protects the red blood cells from sickling. When the infant is around 4 to 5 months of age, the baby or fetal haemoglobin is replaced by sickle hemoglobin and the cells begin to sickle. SCD is a disease that worsens over time. Treatments are available can prevent complications and lengthen lives of those who have this condition. The treatment options can be different for a person depending on symptom’s severity. Hydroxyurea (pronounced hye droks ee yoor EE a) is a medicine that can decrease several complications of SCD. This treatment is safe if given by medical specialists experienced in caring for patients with SCD. Side effects of taking hydroxyurea during pregnancy or for a long time are not completely known. The Food and Drug Administration approved a new medicine to reduce the number of sickle cell crises in adults and children older than age five; it is called L-glutamine. Another treatment, which can actually cure SCD, is a stem cell transplant (also called a bone marrow transplant); this procedure infuses healthy cells, called stem cells, into the body to replace damaged or diseased bone marrow (bone marrow is the center of the bone where blood cells are made). Although transplants of bone marrow or blood from healthy donors are increasingly used to successfully cure SCD, they require a matched donor (a person with similar, compatible bone marrow), and transplants sometimes cause severe side effects and occasional life-threatening illness or death. People with SCD and families should ask their doctors about benefits and risks of treatment options.

Sickle Cell Jaundice

Sickle cell jaundice bilirubin is released byproduct of red blood cells destroyed. The liver must process bilirubin to be excreted as bile into gut for digestion and passed out in the stools or urine. Jaundice occurs when there is too much bilirubin produced by too many red blood cells destroyed. The liver fails to process bilirubin in tummy so abdomen becomes swollen because of a build-up of fluid ascites. Liver and spleen may be enlarged plus unexcreted pile of dead red cells blocks passage of bile into gut. Jaundice disease is assessed and treated with significant symptoms of tiredness, ankle swelling, and also gastrointestinal bleeding, coma, confusion, ascites, etc. Clinical investigations show causes of jaundice increased bilirubin production increase of red blood cells destroyed. So haemolysis collection of blood in tissue red blood cell destroyed cause tiredness or lethargy called haemolyticanaemia. Failure of the liver to process bilirubin excretion diseases affects liver as viral infection, genetic diseases, excessive accumulation of chemicals (copper and iron. The disease Gilbert’s syndrome is a genetic disease causing jaundice by this method. Blockage of passage of bile into gut causes gallstones in bileduct of liver. Accumulation of gallstones requires the removal by surgery.

Jaundice Assessment

Complete jaundice assessment includes yellow eyes seen during clinical history, clinical examination, general or specific investigations. Review of clinical history and a complete routine medical history needs to be obtained. Medical history gives the causes of jaundice including pale stool, very dark urine, itchiness, gallbladder pain, tummy pain or others. A thorough general examination will be carried out specifically, liver and spleen should be felt for an enlargement. Other features include signs of anaemia lack of red blood cells in the body. A routine blood test checks of liver, blood system. The urine is tested to find exact cause in specific investigations by ultrasound for liver and tummy, CT of tummy, or direct visualisation of bile ducts in the tummy. A sample of liver tissue may be required for diagnosis in liver biopsy sometimes.

Treatment of Jaundiced Liver

Treatment of jaundice varies according to causes. A haematologist specialist in blood system, surgeon or physician is involved in treating causes of jaundice. Read more about liver and take care of yourself because the rate young people suffer from kidney disease is alarming. As a result some end up in Hospital on life support with kidney problems but can avert the menace of kidney disease.

TOP 6 CAUSES OF KIDNEY DISEASE:

1. Delay going to a toilet. Keeping your urine in your bladder for too long is a bad idea. A full bladder can cause bladder damage as urine in the bladder multiplies bacteria quickly. Once the urine refluxes back to the ureter and kidneys, the toxic substances can result in kidney infections, then urinary tract infections, nephritis, uremia and sepsis. When nature calls do it soon as you can.

2. Eating too much salt. You should eat no more than 5.8 grams of salt daily.

3. Eating too much meat. Too much protein in your diet is harmful for your kidneys. Protein digestion produces ammonia as a toxin very destructive to your kidneys. Too much meat than body needs equals more kidney damage.

4. Drinking too much caffeine. Caffeine is a component of many sodas and soft drinks. It raises your blood pressure and your kidneys start suffering. So you should cut down the amount of coke you drink daily.

5. Drinking water. Our kidneys should be hydrated properly to perform their functions well. If not drinking enough water the toxins can start accumulating in the blood, as there isn’t enough fluid to drain them through kidneys. Drink more than 10 glasses of water daily. An easy way to check if you are drinking enough water: look at the colour of your urine; the lighter the colour, the better.

6. Early treatment. Treat all your health problems quickly properly and have health checks regularly.  Help yourself God will protect you and your family from every disease.

(3) Avoid Tablets as very dangerous:
* D-cold
* Vicks Action-500
* Actified
* Coldarin
* Cosome
* Nice
* Nimulid
* Cetrizet-D
They contain Phenyl Propanol-Amide PPA causes strokes so banned in USA.

* Doctors in United States have found new cancer in human beings, caused by Silver Nitro Oxide. Whenever you buy recharge cards, don’t scratch with your nails, as it contains Silver Nitro Oxide coating and can cause skin cancer.

Important Health Tips:

1. Answer phone calls with the left ear.

2. Don’t take medicine with cold water.

3. Don’t eat heavy meals after 5pm.

4. Drink more water in morning, less at night.

5. Best sleeping time is 10pm to 4 am.

6. Don’t lie down immediately taking medicine or after meals.

7. If phone’s battery is low to last bar do not answer phone because radiation is 1000 times stronger. Knowledge is power.

Signs or symptoms of acute liver failure include:

  • Yellowing of skin and hands, feet
  • Yellow eyeballs jaundiced
  • Pain in upper right abdomen
  • Abdominal swelling
  • Nausea
  • Vomiting
  • General sense of feeling sick unwell malaise
  • Disorientation or confusion
  • Sleepiness

When to see a doctor

Acute liver failure can develop quickly in an otherwise healthy person and life-threatening. If one suddenly developed yellowing of eyes or skin; tenderness in upper abdomen or unusual changes in mental state, personality or behaviour seek medical attention right away.dreamstime_s_73450142-356x187

Blood Cells & Blood Coagulation

Pluripotential cells in bone marrow differentiate into red blood cells, white cells and platelets. The Immune system  impacts red and white cells. And recent advances help understand coagulation in the heterogeneous group of diseases, thrombotic microangiopathies (TMA) characterized by microangiopathic hemolytic anaemia thrombocytopenia platelet clumping in microcirculation ischemic organ dysfunction neurologic symptoms. Increased thrombosis was reported in different hemolytic anaemia (HA), particularly in sickle cell disease (SCD), and thalassemia. The different patho-physiologies, hemolysis have the procoagulant condition. The mechanism involves abnormal red blood cell (RBC) properties. And the increased plasma concentrations of microparticles and a release of cell-free haemoglobin RBC arginase result in impaired nitric oxide (NO) bioavailability, increased blood concentration of oxidants, endothelial dysfunction. Major clinical consequence increase developing venous thrombosis, clinical sequelae of hemolysis symptom by NO depletion increased cell free plasma haemoglobin. Hemoglobinemia feature of the HA possibly contributing factor to explain clinical manifestation’s thrombotic microangiopathies (TMAs) characterized by microangiopathic HA and thrombocytopenia. The condition characterising intravascular hemolysis specific symptoms seen cell-free plasma haemoglobin sequalae. Conditions such as SCD and thalassemia syndromes and hemolytic conditions with substantial intravascular hemolysis. SCD, and the thalassemia represent common genetic disorders worldwide. Though different patho-physiologies, patients with both diseases share clinical manifestations, including thrombotic complications. So stroke in patients caused by large-vessel obstruction superimposed thrombosis, is one of the major complications in SCD. Pulmonary hypertension (PAH) is a life-threatening complication in SCD, as documented by echo-cardiography (pulmonary artery pressure [PAP] > 30%) in approximately 30% adult patients with SCD screened. Autopsy showed evidence of new and old thrombi in pulmonary vasculature in up to 75% of SCD patients at the time of death. A recent report based on data by National Hospital Discharge Survey in U.S. shows patients with SCD younger than 40 years old had higher discharge diagnosis of pulmonary embolism than African Americans without SCD (0.44% vs 0.12% the prevalence of deep venous thrombosis (DVT) was similar. National In-patient Sample from the Healthcare Cost and Utilization Project of Agency for Healthcare Research and Quality, from 2000 to 2001, reported SCD is a significant risk factor for pregnancy-related venous thromboembolism, with an odds ratio of 6.7 (95% confidence interval: 4.4–10.1. The thrombophilic status in SCD has been well documented as multifactorial, involving hemostatic changes, activation of the coagulation cascade and endothelial activation as shown by elevated levels of endothelial adhesion proteins (ICAM-1. ELAM-1,VCAM-1, von Willebrand factor [VWF] and thrombomodulin). Intimal hyperplasia was found in a variety of vascular beds, including pulmonary, renal, splenic, and placental vessels, and in arterioles adjacent to leg ulcers of patients with SCD. Most SCD-related complications said to be caused by the microvascular occlusion and ischemic tissue necrosis following adhesion of erythrocytes (RBCs) and other cellular elements to vascular endothelium. So clinical series describe occurrence of DVT, pulmonary embolism and portal vein thrombosis in patients with β-thalassemia major and β-thalassemia intermedia. In a recent survey of 8860 patients with β-thalassemia in the Mediterranean region and Iran, the overall prevalence of various thrombotic events was 1.65%, precisely 0.9% in thalassemia major and 4.0% in thalassemia intermedia. Was common in SCD, stroke was reported in patients with β-thalassemia major from Greece and Italy an incidence of 20% and 2%,  patients with β-thalassemia hemoglobin E (HbE) disease. Complication occurs commonly in the patients not regularly transfused. Evidence of asymptomatic brain damage reported by magnetic resonance imaging in patients with β-thalassemia intermedia and is inversely correlated with Hb level and increasing age. PAH is increasingly recognized as part of the clinical spectrum for adult β-thalassemia patients, with a frequency ranging from 10% to 74%; the overall higher rate in thalassemia intermedia. Regular transfusions thought to reduce the risk of thrombosis in thalassemia. In recent study, Singer et al found PAH in transfused patients with thalassemia major, most of whom splenectomized, suggesting regular transfusion does not prevent PAH, thrombotic complications. Several factors implicated pathogenesis of the hypercoagulable state, specific changes in lipid membrane composition of abnormal RBCs increased expression negatively charge phosphatidylserine outer surface. Postsplenectomy thrombocytosis, cardiac dysfunction, liver dysfunction lead to protein C and protein S reduction. Suggest inefficient spleen, hematologic hemolytic diseases contribute to an increased propensity to thromboembolic complications. Both β-thalassemia or sickle cell anemia, have a high proportion of patients without splenic function due to surgical splenectomy or due to functional hyposplenism. In a series of 83 patients with β-thalassemia intermedia followed for 10 years, 29% developed pulmonary embolism, DVT of lower extremities and portal vein thrombosis. Development of complications attributed to presence of high platelet counts after splenectomy. Moderate thrombocytosis in the older children, adults with SCA a consequent loss of splenic sequestration autosplenectomy in patients. Literature on relationship between splenectomy or autosplenectomy and thrombosis in SCA is scant. Specific features of thrombotic complications in patients with SCD and thalassemia share similar pathogenesis. Intravascular hemolysis is a common feature of both SCD and thalassemia. Recent evidence associates chronic intravascular hemolysis with a state of endothelial disfunction.

Red Blood Cells

The major stimulus to red blood cell (RBC) production erythropoetin, which is produced in the kidney. Anaemia is decrease in number or concentration of red blood cells amount of concentration of haemoglobin as a common inducer of erythropoetin production. It is not the number or concentration of RBCs that stimulates erythropoetin production, but decreased oxygenation of the blood. The number of red blood cells increase in chronic hypoxia as occurs in those who live at high altitudes. Effectiveness of the red blood cell in carrying oxygen depends on oxygen supply, number of red blood cells and health of red cells:

1) In aplastic anemia, the marrow as a whole is suppressed, by radiation or drugs. Red cells and other blood cells decrease in number (pancytopenia) in aplastic anemia.

2) Anaemia develops from significant blood loss.

3) If iron, an important ingredient of the haemoglobin molecule is deficient in the diet, the patient develops an iron deficiency anaemia. Iron is transported in blood by plasma protein transferrin, stored intracellularly on the protein, ferritin. Deficiency of transferrin results in an iron deficiency anaemia.

4) Vitamin Bu and folic acid important in synthesis of DNA, in development of RBCs from their precursor cells in the marrow. A deficiency of vitamin B12 or folic acid leads to megaloblastic anaemia in which the RBCs are large, fragile and short-lived. Intrinsic factor, produced by parietal cells in the gastric mucosa, normally combines with vitamin B12, protecting it from gastric digestion, and facilitates its transport across intestinal mucosal membrane. Lack of intrinsic factor, results in a megaloblastic anaemia (pernicious anaemia by failure of B12 absorption.

5) Defects in structure of haemoglobin may be responsible for the anemia. In sickle cell anemia, a recessive gene results in abnormal haemoglobin, which distorts the red cells into a sickle shape in states of low oxygenation. The RBC becomes very fragile, is short-lived, and can clog blood vessels. About 8% of the black population carries the gene. Individuals with the heterozygous state typically are normal, although sickling can occur in marked states of hypoxia. True sickle cell anemia, the homozygous state, occurs in about 0.3% of blacks.

Read more about treatment guidelines »

Hand-Foot Syndrome

Swelling in the hands and feet usually is the first symptom of SCD. This swelling, often along with a fever, is caused by the sickle cells getting stuck in the blood vessels and blocking the flow of blood in and out of the hands and feet. One is at a higher risk of developing blood clots when blood pools in the lower extremities. Elevating the feet and legs will allow veins to return blood to the heart more efficiently and thus reduce the chances of clotting. Those who expect to be bedridden for a long time, such as after surgery or an illness, should put blocks under the foot of a bed to elevate the legs, keeping them slightly higher than heart. Alternatively, placing pillows under one’s lower half will give the same result.

Treatment

The most common treatments for swelling in hands and the feet are pain medicine and an increase in fluids, such as water. Those going on long flight planning for surgery, or other actions that put them at risk for blood clotting, drinking plenty of water can reduce the chance of developing subsequent clots. Proper hydration prevents blood clots in a variety of ways; it increases fluid in blood vessels, diluting the ratio of blood cells and reducing viscosity, lowering risk of clotting. Additional liquid washes away irritants in bloodstream damaging endothelium and blood cells. Blood clot is natural response to damage, washing away toxins significantly lowers risk. Choose water over juices and sodas high sugar liquids leads to dehydration.

Do You Use the Emergency Department for Care of SCD?

Pain “Episode” or “Crisis”

Pain is the most common complication of SCD, and the number 1 reason that people with SCD go to the emergency room or hospital. When sickle cells travel through small blood vessels, they can get stuck and clog the blood flow. This causes pain that can start suddenly, be mild to severe, and can last for any length of time.

Prevention

There are simple steps that people with SCD can take to help prevent and reduce the number of pain crises, including the following:

  • Drink plenty of water.
  • Try not to get too hot or too cold.
  • Try to avoid places or situations that cause exposure to high altitudes (for example, flying, mountain climbing, or cities with a high altitude).
  • Try to avoid places or situations with exposure to low oxygen levels (for example, mountain climbing or exercising extremely hard, such as in military boot camp or when training for an athletic competition).
  • Adults with severe SCD can take a medicine called hydroxyurea to help reduce the number of pain crises.
    • People taking hydroxyurea are checked often by a doctor to prevent complications, including an increased risk of infections.
  • Research shows that babies and children with SCD can also benefit from hydroxyurea therapy.
Treatment

Most pain related to SCD can be treated with over the counter pain medications such as ibuprofen and aspirin. Some people who have severe pain are given opioid (i.e. morphine) medications daily, with additional pain medication. Some people may be admitted to the hospital for intense treatment.

Fast Fact

Taking iron supplements will not help people with sickle cell disease. This type of anemia is not caused by too little iron in the blood; it’s caused by not having enough red blood cells. In fact, taking iron supplements could harm a person with sickle cell disease because the extra iron builds up in the body and can cause damage to the organs.

Anaemia

Anaemia is very common complication of SCD. With SCD, the red blood cells die early. This means there are not enough healthy red blood cells to carry oxygen throughout body. When this happens, a person might have:

  • Tiredness
  • Irritability
  • Dizziness and lightheadedness
  • A fast heart rate
  • Difficulty breathing
  • Pale skin color
  • Jaundice (yellow color to the skin and whites of the eyes)
  • Slow growth
  • Delayed puberty
Treatment

Blood transfusions are used to treat severe anemia. A sudden worsening of anemia resulting from infection or enlargement of the spleen is a common reason for a transfusion. Multiple blood transfusions, however, might cause health problems because of the iron content of blood. Iron overload, called hemosiderosis, can damage liver, heart, pancreas and other organs, leading to diseases such as diabetes mellitus. Iron chelation therapy should be started in patients with SCD receiving regular blood transfusions to reduce excess iron levels. 

Nurse giving a little girl an immunization.

Infection

People with SCD, especially infants and children, are more at risk for infections, especially those due to bacteria with capsules because of damage to the spleen. Pneumonia is a leading cause of death in infants and young children with SCD.

Prevention

Vaccines can protect against harmful infections.

  • Washing your hands is one of the best ways to help prevent getting an infection. People with SCD, their family, and other caretakers should wash their hands with soap and clean water many times each day.
  • Because bacteria in some foods can be especially harmful to children with SCD, food should be prepared safely.
  • Vaccines can protect against harmful infections. Children with SCD should get all regular childhood vaccines, plus a few extra. Adults should have the flu vaccine every year, as well as the pneumococcal vaccine and any others recommended by a doctor.
  • Take penicillin (or other antibiotic prescribed by a doctor) every day until at least 5 years of age.

See a tip sheet on how to help prevent infection »

Treatment

Infections are treated with antibiotic medicines and sometimes blood transfusions. At the first sign of an infection, such as a fever, it is important to see a doctor right away as this may represent a medical emergency for people with SCD. Early treatment of infection can help prevent problems.

Chest x-ray

Acute Chest Syndrome

This can be life-threatening and should be treated in a hospital. Symptoms and signs are similar to pneumonia. Signs and symptoms include chest pain, coughing, difficulty breathing, and fever. Blood clot travels to lungs doctors call pulmonary embolism. Clots reach lungs if small is non-life threatening but smaller clots causes substantial damage to lungs. If clot is large, can stifle proper blood flow and become deadly, so quick treatment is essential. So most common symptom to look for is sudden shortness of breath; if individual is short of breath or lacks physical movement is suffering from pulmonary embolism. A condition causes patient to experience chest pain, breathing problems, heart palpitations. In some cases, a pulmonary embolism causes one to cough up blood as well.

Prevention

Adults with severe SCD can take a medicine called hydroxyurea to help prevent acute chest syndrome. People taking hydroxyurea monitored closely with regular blood testing and dose adjustments to prevent complications. A person on bed rest or recent surgery can use an incentive spirometer, also called “blow bottle,” to help prevent acute chest syndrome.

Treatment

Depending on cause, treatment might include oxygen, medicine to treat an infection, medicine to open up airways to improve air, and blood transfusions. Cut down on salts and fatty cholesterol because salt irritates endothelium or inner lining of veins and arteries. The blood vessels do not work efficiently in moving blood around body. This leads to blood pooling in lower extremities, where it is more likely to clot. Damage to endothelium makes blood cells more to stick to walls of vessels, increasing the risk of clots. Excessive salt intake is harmful to the cardiovascular system in a variety of ways, with blood clots one of the more significant risks. Decreasing salt intake, cutting out all canned and processed foods significantly reduces the risk of blood clots.

Splenic Sequestration

This can be life-threatening and should be treated in a hospital. It happens when a large number of sickle cells get trapped in the spleen and cause it to suddenly get large. Symptoms include sudden weakness, pale lips, fast breathing, extreme thirst, abdominal (belly) pain on the left side of body, and fast heartbeat.

Parents of a child with SCD should learn how to feel and measure the size of their child’s spleen and seek help if the spleen is enlarged.

Prevention

For those who have had a very severe, life-threatening episode of splenic sequestration or who have had many episodes in the past, it might be necessary to have regular blood transfusions or the spleen can be removed (called splenectomy) to stop it from happening again.

Treatment

Treatment typically is a blood transfusion. This should be done in consultation with a blood specialist as patients sometimes become overloaded with fluid when the blood is released from the spleen. Removal of blood may be necessary to prevent this happening.

Young girl getting eyes checked at the eye doctor

Vision Loss

Vision loss, including blindness, can occur when blood vessels in the eye become blocked with sickle cells and the retina (the thin layer of tissue inside the back of the eye) gets damaged. Some patients develop extra blood vessels in the eye from the lack of oxygen.

Prevention

People with sickle cell disease should have their eyes checked every year to look for damage to retina. If possible, this should be done by an eye doctor who specializes in diseases of the retina.

Treatment

If the retina is damaged by excessive blood vessel growth, laser treatment often can prevent further vision loss.

Leg Ulcers

This usually occurs on the lower part of the leg. They happen more often in males than in females and usually appear from 10 through 50 years of age. A combination of factors cause ulcer formation, including trauma, infection, inflammation, and interruption of the circulation in the smallest blood vessels of the leg.

Treatment

Leg ulcers can be treated with medicated creams and ointments. Leg ulcers can be painful, and patients can be given strong pain medicine. Management of leg ulcers could also include the use of cultured skin grafts. Treatment is provided in specialized centers. Bed rest and keeping leg or legs raised to reduce swelling helpful though not always possible.

Stroke

A stroke can happen if sickle cells get stuck in a blood vessel and clog blood flow to the brain. About 10% of children with SCD will have a symptomatic stroke. Stroke can cause learning problems and lifelong disabilities.

Prevention

Children who are at risk for stroke can be identified using a special type of exam called, transcranial Doppler ultrasound (TCD). If the child is found to have an abnormal TCD, a doctor might recommend frequent blood transfusions to help prevent a stroke. People who have frequent blood transfusions must be watched closely because there are serious side effects. For example, too much iron can build up in the body, causing life-threatening damage to the organs.

Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)

Sickling of red cells can increase blood coagulation and induce an increased risk of blood clot in a deep vein (DVT), or in the lung (PE) if the blood clot moves from the deep veins. People with SCD have a high chance of developing DVT or PE. DVT and PE can cause serious illness, disability and, in some cases, death.

Prevention and Treatment

Medication is used to prevent and treat DVT and PE. PE requires immediate medical attention. For more information on DVT and PE visit https://www.cdc.gov/ncbddd/dvt/index.html.

Other Possible Complications

  • Damage to body organs (like the liver, heart, or kidneys), tissues, or bones because not enough blood is flowing to the affected area(s).
  • Malnutrition and growth retardation among adolescents can cause a delayed onset of puberty and, in males, infertility.
  • Gallstones.
  • Painful erection of the penis, called priapism, can last less than 2 hours or more than 4 hours. If it lasts more than 4 hours, the person should get urgent medical help. It can lead to impotence.
  • A very rare form of kidney cancer (renal medullary carcinoma) has been associated with sickle cell trait.

Links to Other Websites

Sickle Cell Disease Association of America

National Heart Lung and Blood Institute Clinical Trials

Be The Match – Bone Marrow Transplantation

Reblogged as previously published